A week or two ago, I got into a conversation on Twitter about technical debt, and someone shared this superb video by Ward Cunningham (youtube). Here is Ward’s Interview website.

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Waterfall, agile, developer or operations, devops, managers, CTOs… everyone should watch this video, for it cuts to the heart of the challenges we face doing modern software development, in a fast paced and always changing environment.

Though it’s not mentioned in the video, I would argue using an ORM is an expensive form of debt, one that …

University of Montreal Tracks Genomic Data With Tokutek’s TokuDB.

Faster insertion rates, improved scalability and agility support lab’s fast growing research database as it grows from 100s of GBs to 1 TB and beyond.

Issue addressed: MySQL database used for genomic research must be able to quickly ingest huge amounts of incoming data – hundreds of thousands of records every day. It also must be able to retrieve data quickly in response to a diverse set of research requests.

Enabling the Hunt for New Cures for Diseases by Seamlessly Processing Billions of Mutations in Epidemiology Records

The Organization: The The Philip Awadalla Laboratory is the Medical and …