I only recently found out about GigaOm's upcoming Net:Work conference.  It's held December 9 at UCSF Mission Bay conference center.  While the name of the conference is a bit ambiguous, the actual area of focus is very clear: how will we collaborate in the 21st century?  

The impact of smartphones, tablet computing, social networks, Software-as-a-Service and Cloud computing is just starting.  As a result, I think there are tremendous opportunities for startup companies to disrupt existing markets with more modern, lightweight applications