Async and PXC
A common question I get about Percona XtraDB Cluster is if you can mix it with asynchronous replication, and the answer is yes! You can pick any node in your cluster and it can either be either a slave or a master just like any other regular MySQL standalone server (Just be sure to use log-slave-updates in both cases on the node in question!). Consider this architecture:
However, there are some caveats to be aware of. If you slave from a cluster node, there is no built in mechanism to fail that slave over automatically to another master node in your cluster. You cannot assume that the binary log positions are the same on all nodes in your cluster (even if they start binary logging at the same time), so you can’t issue a CHANGE MASTER without knowing the proper binary log position to start at.